Products Description of Thiophene-3-ethanol CAS#13781-67-4
Thiophene-3-ethanol, alternatively named 3-thiopheneethanol, appears as clear liquid ranging from colourless to faint yellow at ambient temperature. Its molecular formula is C6H8OS and the molecular weight equals around 128.19.
Its measured physical parameters contain a boiling-point range of 110-111°C under 14 mmHg, density value of 1.144 g/mL and refractive index at 1.552. The hydroxyl group on its thiophene ring brings favourable reaction activity. This chemical acts as a vital building block for pharmaceutical manufacture and general organic synthesis work, and it is well recognised for producing clopidogrel and other related medicinal substances.
Thiophene-3-ethanol Chemical Properties
| Boiling point | 110-111 °C14 mm Hg(lit.) |
| density | 1.144 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.552(lit.) |
| Fp | 199 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| pka | 14.92±0.10(Predicted) |
| Specific Gravity | 1.144 |
| color | Clear colorless to yellow-brown |
| Water Solubility | Sparingly soluble in water(0.059 g/L at 25°C). |
| BRN | 107080 |
| InChIKey | YYPNNBPPDFTQFX-UHFFFAOYSA-N |
| LogP | 1.07 |
| CAS DataBase Reference | 13781-67-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Thiopheneethanol(13781-67-4) |
| Safety Statements | 23-24/25 |
| WGK Germany | 3 |
| F | 10 |
| HS Code | 29349990 |
Product Application of Thiophene-3-ethanol CAS#13781-67-4
Thiophene-3-ethanol serves as the essential synthetic precursor for pharmaceutical grade production. The hydroxyl group linked to the thiophene ring permits diverse chemical-modification reactions to construct heterocyclic frameworks of active substances.
In addition to the well-known anti-platelet medicine clopidogrel, this raw material may be converted into ticlopidine, thiopheneethylamine and other thiophene-based substances. It is also applied in laboratory-level organic research to prepare new-style heterocyclic intermediates for potential drug-candidate screening work.
