Product Description of 2'-Hydroxyacetophenone CAS#118-93-4
Also named ortho-hydroxyacetophenone, 2'-Hydroxyacetophenone belongs to organic chemicals with the molecular formula C₈H₈O₂. This substance presents pale-yellow liquid form at ambient temperature. It enjoys extensive utilisation in multiple industrial sectors, mainly covering perfume raw-material processing and pharmaceutical-related manufacture.
2'-Hydroxyacetophenone Chemical Properties
| Melting point | 3-6 °C(lit.) |
| Boiling point | 213 °C717 mm Hg(lit.) |
| density | 1.131 g/mL at 25 °C(lit.) |
| vapor density | 4.7 (vs air) |
| vapor pressure | ~0.2 mm Hg ( 20 °C) |
| refractive index | n20/D 1.558(lit.) |
| FEMA | 3548 | 2-HYDROXYACETOPHENONE |
| Fp | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | 0.2g/l |
| form | Liquid |
| pka | 10.06(at 25℃) |
| color | Clear yellow to brown |
| Odor | at 10.00 % in dipropylene glycol. phenolic sweet hawthorn tobacco honey herbal |
| Odor Type | phenolic |
| explosive limit | 0.98-11.8%(V) |
| Water Solubility | slightly soluble |
| JECFA Number | 727 |
| BRN | 386123 |
| LogP | 1.92-1.97 at 25℃ |
| Dissociation constant | 10.06-10.25 at 20-25℃ |
| CAS DataBase Reference | 118-93-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 1-(2-hydroxyphenyl)-(118-93-4) |
| EPA Substance Registry System | 2'-Hydroxyacetophenone (118-93-4) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-36/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| RTECS | AM8575000 |
| F | 8 |
| Hazard Note | Harmful/Irritant |
| TSCA | Yes |
| HS Code | 29145000 |
| Toxicity | LD50 orally in Rabbit: 2127 mg/kg LD50 dermal Rat > 2000 mg/kg |
Product Applications of 2'-Hydroxyacetophenone CAS#118-93-4
2'-Hydroxyacetophenone (CAS#118-93-4) fits numerous industrial-grade purposes:
Flavor and Fragrance Sector：This raw-material gets frequently incorporated into flavour recipes for cherry pit, cinnamon, rum, tobacco, coumarin and tropical-fruit aromas.
Pharmaceutical Synthetic Intermediates：It works as a building-block substance when preparing chemical compounds with antibacterial and anti-tumour properties.
Organic-chemistry Manufacture：The compound is extensively utilised as processing intermediate or starting material during organic synthetic reactions.
Handling Recommendations：Keep the commodity under 30 °C for stable storage. Operate cautiously and wear proper protective gear so as to avoid skin irritation and eye exposure.
